Overview of High Fluorescence Ratio (HFR), Middle Fluorescence Ratio (MFR), Mean Cell Volume (MCV), and Mean Cell Hemoglobin (MCH) in Patients with Hemoglobin Levels Below 8
DOI:
https://doi.org/10.56359/igj.v4i3.635Keywords:
Anemia, HFR, MFR, MCV, MCHAbstract
Background & Objective: Anemia occurs when a person has a deficiency of red blood cells or hemoglobin, with the threshold for anemia defined as hemoglobin levels below 12 g/dl. This condition is commonly found in medical practice, especially anemia caused by iron deficiency, vitamin B12 deficiency, folate deficiency, chronic disease, or bleeding. This study aimed to describe the high fluorescence ratio (HFR), middle fluorescence ratio (MFR), mean cell volume (MCV), and mean cell hemoglobin (MCH) in patients with hemoglobin levels below 8.
Method: This was a descriptive study using purposive sampling, with a total of 30 respondents.
Result: The results showed that 9 patients (30%) had high HFR and MFR with normal MCV and MCH; 6 patients (20%) had normal HFR and MFR with normal MCV and MCH; 5 patients (17%) had high HFR and MFR with low MCV and MCH; 3 patients (10%) had high HFR, normal MFR, and low MCV and MCH; 2 patients (7%) had high HFR and MFR with normal MCV and low MCH; 2 patients (7%) had normal HFR and MFR with low MCV and normal MCH; 1 patient (3%) had normal HFR and MFR with low MCV and MCH; 1 patient (3%) had normal HFR, high MFR, with low MCV and normal MCH; and 1 patient (3%) had normal HFR, low MFR, and normal MCV and MCH.
Conclusion: This study indicates that most patients with severe anemia (Hb < 8) showed a relatively good regenerative response (as indicated by high HFR and MFR), although variations in anemia types were also observed based on MCV and MCH values, reflecting possible different causes and classifications of anemia.
Downloads
References
atika, P. (2011). anemia dan anemia kehamilan.
Eva Ayu, M. (2023). HEMATOLOGI (M. Eva Ayu (Ed.)).
Laboratorium Fisiologi Struktur dan Perkembangan Hewan FMIPA Universitas Brawijaya. (2019). Prosedur Operasi Baku Analisis Data Flow Cytometry. Jurusan Biologi FMIPA Universitas Brawijaya, Gambar 1, 1–5. https://biologi.ub.ac.id/fisiologi/wp-content/uploads/sites/9/2019/04/Analisis-Data-Flow-cytometry_id.pdf
Lfr mfr hfr (hal. 8). (n.d.).
Nasruddin, H., Faisal Syamsu, R., & Permatasari, D. (2021). Angka Kejadian Anemia Pada Remaja di Indonesia. Cerdika: Jurnal Ilmiah Indonesia, 1(4), 357–364. https://doi.org/10.59141/cerdika.v1i4.66
Obstfeld, A. E., Davis, B. H., Han, J. Y., & Urrechaga, E. (2024). Report of the International Council for Standardization in Haematology working group for standardization of reticulocyte parameters. International Journal of Laboratory Hematology, 46(2), 266–274. https://doi.org/10.1111/ijlh.14209
robert b, kileen. (2023). No Title. anemia akut. https://www.ncbi.nlm.nih.gov/books/NBK537232/?utm_source=chatgpt.com
Setiawan, D., Nurjamilah, R., Firdaus, N. R., Istianah, E. T., & Nurmalasari, A. (2024). STABILITAS POOLED SERA SEBAGAI ALTERNATIF BAHAN KONTROL POSITIF PEMERIKSAAN C-REACTIVE PROTEIN. Prosiding Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia, 3, 378-388.
Setiawan, D. (2023). KONSENTRASI ANTI-HBs PADA KARYAWAN RUMAH SAKIT YANG TELAH MELAKUKAN VAKSINASI HEPATITIS B. Masker Medika, 11(1), 55-61.
Suburwibowogmailcom, K. P. (2024). Gambaran MCH , MCV dan MCHC Pada Ibu Hamil Trimester II di Puskesmas Wonokerto I Kabupaten Pekalongan Subur Wibowo Akademi Analis Kesehatan Pekalongan Anisah Fauziyah Akademi Analis Kesehatan Pekalongan Terdapat menderita anemia pada kehamilannya .( Apria. 2(1).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Nurul Wahidah Lestari, Bekti Mastiadji
This work is licensed under a Creative Commons Attribution 4.0 International License.
