Literature Review: Delayed Umbilical Cord Clamping on Hemoglobin Levels in Newborns

Authors

  • Resna Litasari STIKes Muhammadiyah Ciamis
  • Neli Sunarni STIKes Muhammadiyah Ciamis
  • Dini Ariani STIKes Muhammadiyah Ciamis

DOI:

https://doi.org/10.56359/igj.v4i2.733

Keywords:

BBL, Hemoglobin, Delayed Cord Cutting

Abstract

Introduction & Objective: Neonatal anemia is a common health problem, particularly in developing countries, and contributes to increased morbidity and mortality in infants. One effective intervention that can be implemented immediately after birth is delayed cord clamping, which involves delaying the clamping of the umbilical cord for 1–3 minutes to allow for blood transfusion from the placenta to the infant. This practice is associated with increased hemoglobin levels in newborns.

Method: This study is a literature review analyzing seven selected research articles published between 2019 and 2024, from both national and international journals. Inclusion criteria included experimental or quasi-experimental studies evaluating the effects of delayed cord clamping on hemoglobin levels and newborns. Data were analyzed narratively and comparatively.

Result: All analyzed studies showed that delayed umbilical cord clamping has a positive impact on increasing hemoglobin levels and the hematological status of newborns. Newborns who underwent delayed umbilical cord clamping had higher hemoglobin, hematocrit, and iron stores compared to those who had their umbilical cord clamped earlier. Some studies also noted improved blood pressure stability and organ perfusion, particularly in preterm infants.

Conclusion: Delayed cord clamping is a simple, safe, and effective intervention that can increase hemoglobin levels and improve the hematological status of newborn infants. The routine implementation of delayed cord clamping should be considered in delivery protocols as a preventive measure against neonatal anemia.

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References

Arum Dilafa, R., Rahardjo, S. S., & Murti, B. (2023). Maret Meta-Analysis the Effect of Cord Clamping Time on Hemoglobin Elevation in Newborn Infants. Journal of Maternal and Child Health, 03, 347–355. https://doi.org/10.26911/thejmch.2023.08.03.09

Andersson, O., Hellström-Westas, L., Andersson, D., & Domellöf, M. (2011). Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: A randomised controlled trial. BMJ (Online), 343(7836), 1244. https://doi.org/10.1136/bmj.d7157

APN. (2017). Buku Acuan Persalinan Normal. JNPK-KR.

Asfarina, I., Wijaya, M., Kadi, F. A., Studi, P., Dokter, P., Ilmu, D., Masyarakat, K., Anak, K., Kedokteran, F., Padjadjaran, U., Rsup, /, & Sadikin, H. (2020). Prevalensi Anemia pada Bayi Baru Lahir Berdasarkan Berat Lahir dan Usia Kehamilan di RSUP Dr. Hasan Sadikin Bandung Tahun 2018 (Vol. 22, Issue 4).

Berihun, G. A., Tesfaye, G., Adissu, W., Adamu, K., Kombe, A. T., Gedefaw, L., & Tadasa, E. (2024). Prevalence and Associated Factors of Anemia among Newborns at Jimma Medical Center, South-west Ethiopia. Journal of Blood Medicine, 15, 129–140. https://doi.org/10.2147/JBM.S443312

Busarira, M. O., Alasbaly, E., & Mbark, M. S. (2019). Effect of Delayed versus Early Cord Clamping on Neonatal Outcomes and Iron Status at 4 Months. Open Journal of Obstetrics and Gynecology, 09(02), 229–241. https://doi.org/10.4236/ojog.2019.92024

Gonnade, N. V., Nikhate, S. D., Bal, H., & Shrivastava, N. (2018). A comparative study of early and delayed cord clamping in term deliveries. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 7(12), 4929. https://doi.org/10.18203/2320-1770.ijrcog20184942

WHO. (2012). Guidelines on basic newborn resuscitation. World Health Organization.

Haider, B. A., Olofin, I., Wang, M., Spiegelman, D., Ezzati, M., & Fawzi, W. W. (2013). Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: Systematic review and meta-analysis. In BMJ (Online) (Vol. 347, Issue 7916). BMJ Publishing Group. https://doi.org/10.1136/bmj.f3443

WHO. (2014). Guideline: Delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes.

Ilmiyani, S. N., Yanti, E. M., & Siswari, B. D. (2023). The Effect of Delayed Cord Clamping (DCC) on Haemoglobin Levels and Oxygen Saturation Levels in Newborns. Babali Nursing Research, 4(3), 420–430. https://doi.org/10.37363/bnr.2023.43241

Kemenkes RI. (2023). Laporan Kinerja Kemenkes RI.

Malik, S., Kapu, M., Kumar Jain, M., Patel, B., & Kabra, N. (2024). Effects of timing of cord clamping on neonatal hemoglobin and bilirubin levels in preterm and term infants—A prospective observational cohort study. PLoS ONE, 19(1 January). https://doi.org/10.1371/journal.pone.0295929

Mena, N., & Mohammed, A. (2023). Effects of Delayed Cord Clamping on Neonatal Hematological Status at Maternity Teaching Hospital in Sulaimani City/Iraq. Mosul Journal of Nursing, 11(2), 316–325. https://doi.org/10.33899/mjn.2023.180108

Ramadhan, A. K., Danianto, A., & Cholidah, R. (2023). Anemia in Pregnancy: Cause and Effect. Jurnal Biologi Tropis, 23(1), 464–470. https://doi.org/10.29303/jbt.v23i1.6074

Nanda, E., Maryana, N., Fadilah, M., Fauzia, A. R., Nurapandi, A., & Marliany, H. (2025). Efficacy of Iron Tablet Supplementation on Hemoglobin Levels in Adolescents: A Systematic Review. Genius Journal, 6(1), 272-283.

Restya, E. R., Lailaturohmag, L., Lukmawati, D., & Septiana, F. (2024). The Effect Of Delaying Umbilical Cord Cutting On Hemoglobin Levels In Newborn Babies. Health Gate, 2(3), 223–227. https://doi.org/10.70111/hg2304

Jafra, B. S., Mehendiratta, S. K., Jafra, P. R., & Jafar, A. (2023). Effect of timing of cord clamping (early vs delayed) on hemoglobin level among newborns: an Indian study. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 12(6), 1775–1779. https://doi.org/10.18203/2320-1770.ijrcog20231553

Santi, M., Wardani, Z., & Permata Sari, N. (2021). Effect of Delayed Cord Clamping on Hemoglobin Levels of Newborn. ARKESMAS, 6(2). https://www.researchgate.net/publication/360559291

Suryani, L. (2019). Efektifitas Waktu Penundaan Pemotongan Tali Pusat Terhadap Kadar Hemoglobin Pada Bayi Baru Lahir Di RS Anutapura Kota Palu. Jurnal Kesehatan Manarang, 5(1). http://jurnal.poltekkesmamuju.ac.id/index.php/m

Setiawan, D., Firdaus, N. R., Ariyadi, R., & Indriastuti, M. (2025). Peningkatan Pemahaman Penyakit Thalasemia pada Anggota PMR Tingkat Wira di SMA Terpadu Ar-Risalah Cijantung IV Kabupaten Ciamis: Increased Understanding of Thalassemia Disease in PMR Members at the Wira Level at Ar-Risalah Integrated High School Cijantung IV Ciamis Regency. PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat, 10(6).

Sutni, A., & Nulhakim, L. (2023). Original Research The Relationship Between Anemia Incidence In Pregnant Mothers And Low Birth Weight Baby Delivery. In International Journal of Nursing and Midwifery Science (IJNMS) (Vol. 7). http://ijnms.net/index.php/ijnms

Triani, A., Maternity, D., & Fitria. (2022). Penundaan pemotongan tali pusat terhadap kadar hemoglobin Pada bayi baru lahir. MJ (Midwifery Journal), 2(1), 41–48.

Xodo, S., Xodo, L., & Berghella, V. (2018). Delayed cord clamping and cord gas analysis at birth. Acta Obstetricia et Gynecologica Scandinavica, 97(1), 7–12. https://doi.org/10.1111/aogs.13233

Zanardo, V., Guerrini, P., Tortora, D., Severino, L., Sandri, A., & Strafece, G. (2023). Effect of early and delayed umbilical cord clamping on placental transfusion in two-step delivery: a randomised clinical trial. https://doi.org/10.21203/rs.3.rs-2858823/v1

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Published

2025-06-01

How to Cite

Litasari, R., Sunarni, N. ., & Ariani, D. . (2025). Literature Review: Delayed Umbilical Cord Clamping on Hemoglobin Levels in Newborns. INDOGENIUS, 4(2), 548–555. https://doi.org/10.56359/igj.v4i2.733

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Section

Literature Review